簡要描述:2號染色體開放閱讀框18抗體免 疫 原;KLH conjugated synthetic peptide derived from human C2orf18/ANT2BP: 231-330/371
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2號染色體開放閱讀框18抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
2號染色體開放閱讀框18抗體 | C2orf18 | GOY-01K4247 |
商品屬性:
英文名稱: C2orf18
中文名:2號染色體開放閱讀框18抗體
別 名;ANT2 binding
protein; ANT2BP; Chromosome 2 open reading frame 18; FLJ20555; S35F6_HUMAN.
研究領域;腫瘤 細胞生物 免疫學 結合蛋白 線粒體
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應;(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 IEM=1:20-200 ICA=1:20-200
ChIP=1:20-200 (石蠟切片需做抗原修復)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;38kDa
細胞定位;細胞漿 細胞膜 線粒體
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human C2orf18/ANT2BP: 231-330/371
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
C2orf18 is a 371 amino acid multi-pass membrane
protein that contains one DUF6 domain and is encoded by a gene that maps to
human chromosome 2p23.3. As the second largest human chromosome, chromosome 2
makes up approximately 8% of the human genome and contains 237 million bases
encoding over 1,400 genes. A number of genetic diseases are linked to genes
on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated
with mutations in the ABCA12 gene. The lipid metabolic disorder
sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare
recessive genetic disorder, Alstr鰉
syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a
probable vestigial second centromere as well as vestigial telomeres, which
gives credence to the hypothesis that human chromosome 2 formed as a result
of an ancient fusion of two ancestral chromosomes, which are still present in
modern day apes. Function: Involved in the maintenance of mitochondrial
membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes
pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a
nucleotide-sugar transporter. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結果是陽性。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務,包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務,如動物免疫、動物飼養(yǎng)、抗體修飾服務(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務。
抗體定制服務:
已注冊商標,主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務,主要面向工業(yè)客戶。
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