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簡(jiǎn)要描述:鈣離子通道a1F亞型抗體免 疫 原;KLH conjugated synthetic peptide derived from human CACNA1F: 1001-1100/1977
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鈣離子通道a1F亞型抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
鈣離子通道a1F亞型抗體 | CACNA1F | GOY-01K1076 |
商品屬性:
英文名稱: CACNA1F
中文名:鈣離子通道a1F亞型抗體
別 名;CACNA 1F; CACNAF;
CACNAF1; Calcium channel voltage dependent alpha 1F subunit; Calcium channel
voltage dependent L type alpha 1F subunit; Cav1.4; Cav1.4alpha1; COD 3; COD3;
CORDX 3; CORDX; CORDX3; CSNB2A; CSNBX 2; CSNBX2; JM 8; JM8; JMC 8; JMC8;
Voltage ated calcium channel subunit alpha Cav1.4; Voltage ependent L ype
calcium channel subunit alpha F; CAC1F_HUMAN.
研究領(lǐng)域;神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 通道蛋白
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;221kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human CACNA1F: 1001-1100/1977
<Extracellular>
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Voltage-dependent Ca2+ channels mediate Ca2+ entry
into excitable cells in response to membrane depolarization, and they are
involved in a variety of Ca2+-dependent processes, including muscle
contraction, hormone or neurotransmitter release and gene expression.Ca2+
currents are characterized on the basis of their biophysical and
pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. L-type
Ca2+ currents initiate muscle contraction, endocrine secretion, and gene
transcription, and can be regulated through second-messenger activated
protein phosphorylation pathways. L-type calcium channels may form
macromolecular signaling complexes with G protein-coupled receptors, thereby
enhancing the selectivity of regulating specific targets. CACNA1F (Calcium channel, voltage-dependent, L
type, alpha 1F subunit) is a subunit of a voltage-dependent calcium channel
complex. Voltage-gated calcium channels mediate the entry of calcium ions
into excitable cells. CACNA1F gives rise to L-type calcium currents.
Long-lasting (L-type) calcium channels belong to the "high-voltage
activated" (HVA) group and are blocked by dihydropyridines (DHP). |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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