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簡要描述：鈣粘蛋白20抗體免 疫 原；KLH conjugated synthetic peptide derived from human Cadherin 20: 301-400/801
產(chǎn)品型號：GOY-01K2437廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：144產(chǎn)品分類
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鈣粘蛋白20抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
鈣粘蛋白20抗體 | Cadherin 20 | GOY-01K2437 |
商品屬性：
英文名稱: Cadherin 20
中文名:鈣粘蛋白20抗體
別 名；Cadherin 20;
cadherin-20; Cadherin 20, type 2; Cdh7; CDH7L3; FLJ37047; CAD20_HUMAN.
研究領(lǐng)域；細胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細胞粘附分子
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；82kDa
細胞定位；細胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human Cadherin 20: 301-400/801
<Extracellular>
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The cadherins are a family of Ca2+-dependent
adhesion molecules that function to mediate cell-cell binding critical to the
maintenance of structure and morphogenesis. Cadherins each contain a large
extracellular domain at the N-terminus, which is characterized by a series of
five homologous repeats, the most distal of which is thought to be responsible
for binding specificity. Cadherin-20, also known as protocadherin gamma B4,
is a member of the protocadherin gamma gene cluster. Expressed primariy in
fibroblasts, cadherin-20 plays a critical role in neuronal cell-cell
connections in the brain. Through its ability to mediate cell-cell adhesion,
caderin-20 is thought to help the body respond to injury by regulating
post-traumatic wound healing. This gene is a type II classical cadherin from the
cadherin superfamily and one of three cadherin 7-like genes located in a
cluster on chromosome 18. The encoded membrane protein is a calcium dependent
cell-cell adhesion glycoprotein comprised of five extracellular cadherin
repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type
II (atypical) cadherins are defined based on their lack of a HAV cell
adhesion recognition sequence specific to type I cadherins. Since disturbance
of intracellular adhesion is a prerequisite for invasion and metastasis of
tumor cells, cadherins are considered prime candidates for tumor suppressor
genes. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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