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簡要描述：CD59重組兔單克隆抗體免 疫 原；KLH conjugated synthetic peptide derived from human CD59
產(chǎn)品型號：GOY-01K1925廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：144產(chǎn)品分類
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CD59重組兔單克隆抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
CD59重組兔單克隆抗體 | CD59 | GOY-01K1925 |
商品屬性：
英文名稱: CD59
中文名:CD59重組兔單克隆抗體
別 名；CD59
glycoprotein; CD59 molecule (CD59 blood group); 1F5 antigen; 20 kDa homologous
restriction factor; MAC-inhibitory protein; Membrane attack complex inhibition
factor; Membrane inhibitor of reactive lysis; MEM43 antigen; MACIF; 1F5; EJ16;
EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5;
HRF-20; MAC-IP; p18-20; CD59_HUMAN.
研究領(lǐng)域；心血管 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 干細(xì)胞
抗體來源；Rabbit
克隆類型；Monoclonal
克 隆 號E10F7
交叉反應(yīng)；Human,
產(chǎn)品應(yīng)用；WB=1:500-2000
IHC-P=1:50-1:100 Flow-Cyt=1:100 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；9kDa
細(xì)胞定位；細(xì)胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human CD59
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene encodes a cell surface glycoprotein that
regulates complement-mediated cell lysis, and it is involved in lymphocyte
signal transduction. This protein is a potent inhibitor of the complement
membrane attack complex, whereby it binds complement C8 and/or C9 during the
assembly of this complex, thereby inhibiting the incorporation of multiple
copies of C9 into the complex, which is necessary for osmolytic pore
formation. This protein also plays a role in signal transduction pathways in
the activation of T cells. Mutations in this gene cause CD59 deficiency, a
disease resulting in hemolytic anemia and thrombosis, and which causes
cerebral infarction. Multiple alternatively spliced transcript variants,
which encode the same protein, have been identified for this gene. [provided
by RefSeq, Jul 2008] Function: Potent inhibitor of the complement membrane attack
complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the
assembling MAC, thereby preventing incorporation of the multiple copies of C9
required for complete formation of the osmolytic pore. This inhibitor appears
to be species-specific. Involved in signal transduction for T-cell activation
complexed to a protein tyrosine kinase. The soluble form from urine retains its specific
complement binding activity, but exhibits greatly reduced ability to inhibit
MAC assembly on cell membranes. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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