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簡要描述：CD98重鏈抗原抗體免 疫 原；KLH conjugated synthetic peptide derived from human CD98: 231-280/630
產(chǎn)品型號：GOY-01K0170廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：149產(chǎn)品分類
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CD98重鏈抗原抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
CD98重鏈抗原抗體 | CD98 | GOY-01K0170 |
商品屬性：
英文名稱: CD98
中文名:CD98重鏈抗原抗體
別 名；4F2; 4F2 cell
surface antigen heavy chain; 4F2 cell-surface antigen heavy chain; 4F2 heavy
chain; 4F2 heavy chain antigen; 4F2_HUMAN; 4F2hc; 4T2HC; Antigen defined by
monoclonal antibody 4F2 heavy chain; Antigen identified by monoclonal
antibodies 4F2 TRA1.10 TROP4 and T43; CD 98; CD98 antigen; CD98 heavy chain;
CD98HC; Heavy chain; Lymphocyte activation antigen 4F2 large subunit; MDU 1;
MDU1; Monoclonal antibody 44D7; NACAE; Slc3a2; Solute carrier family 3
(activators of dibasic and neutral amino acid transport) member 2; Solute
carrier family 3 member 2.
研究領(lǐng)域；細胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 干細胞 轉(zhuǎn)錄調(diào)節(jié)因子 t-淋巴細胞 b-淋巴細胞
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；69kDa
細胞定位；細胞漿 細胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH conjugated
synthetic peptide derived from human CD98: 231-280/630 <Extracellular>
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene is a member of the solute carrier family
and encodes a cell surface, transmembrane protein. The protein exists as the
heavy chain of a heterodimer, covalently bound through di-sulfide bonds to
one of several possible light chains. The encoded transporter plays a role in
regulation of intracellular calcium levels and transports L-type amino acids.
Alternatively spliced transcript variants, encoding different isoforms, have
been characterized. [provided by RefSeq, Nov 2010]. Function: Required for the function of light chain
amino-acid transporters. Involved in sodium-independent, high-affinity
transport of large neutral amino acids such as phenylalanine, tyrosine,
leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1
and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts
as an arginine/glutamine exchanger, following an antiport mechanism for amino
acid transport, influencing arginine release in exchange for extracellular
amino acids. Plays a role in nitric oxide synthesis in human umbilical vein
endothelial cells (HUVECs) via transport of L-arginine. Required for normal
and neoplastic cell growth. When associated with SLC7A5/LAT1, is also
involved in the transport of L-DOPA across the blood-brain barrier, and that
of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell
membrane in tissues such as placenta. Involved in the uptake of methylmercury
(MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and
hence plays a role in metal ion homeostasis and toxicity. When associated
with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular
weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine
(L-CNSO) across the transmembrane. Together with ICAM1, regulates the
transport activity LAT2 in polarized intestinal cells, by generating and
delivering intracellular signals. When associated with SLC7A5, plays an
important role in transporting L-leucine from the circulating blood to the
retina across the inner blood-retinal barrier. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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