簡(jiǎn)要描述:睪丸特異性蛋白57抗體免 疫 原;KLH conjugated synthetic peptide derived from human CEP57: 51-150/500
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睪丸特異性蛋白57抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
睪丸特異性蛋白57抗體 | CEP57 | GOY-01K4629 |
商品屬性:
英文名稱: CEP57
中文名:睪丸特異性蛋白57抗體
別 名;Centrosomal
protein 57kDa; Centrosomal protein of 57 kDa; Cep57; Cep57 protein;
CEP57_HUMAN; FGF2 interacting protein; FGF2-interacting protein; KIAA0092;
MVA2; PIG8; Proliferation inducing protein 8; Testis specific protein 57;
Testis-specific protein 57; Translokin; TSP57.
研究領(lǐng)域;細(xì)胞生物 發(fā)育生物學(xué) 干細(xì)胞 細(xì)胞分化
抗體來(lái)源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Dog, Horse, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;57kDa
細(xì)胞定位;細(xì)胞核 細(xì)胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human CEP57: 51-150/500
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
CEP57 (centrosomal protein 57kDa), also known as
PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both
the nucleus and the cytoplasm, specifically associating with microtubules at
the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that
functions to mediate the mitogenic activity and nuclear translocation of
FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling
pathways. Additionally, CEP57 is thought to play a role in spermatogenesis,
possibly via the indirect regulation of gene expression. Human CEP57 shares
88% sequence identity with its mouse and bovine orthologs, suggesting a
highly conserved role between species. Multiple isoforms of CEP57 exist due
to alternative splicing events. Centrosomal protein which may be required for
microtubule attachment to centrosomes. May act by forming ring-like
structures around microtubules. Mediates nuclear translocation and mitogenic
activity of the internalized growth factor FGF2. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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