簡要描述:C型凝集素結(jié)構(gòu)域家族12成員A抗體免 疫 原;KLH conjugated synthetic peptide derived from human CLEC12A: 61-160/265
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C型凝集素結(jié)構(gòu)域家族12成員A抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
C型凝集素結(jié)構(gòu)域家族12成員A抗體 | CLEC12A | GOY-01K0175 |
商品屬性:
英文名稱: CLEC12A
中文名:C型凝集素結(jié)構(gòu)域家族12成員A抗體
別 名;C-type lectin
domain family 12 member A; C-type lectin-like molecule 1; CL12A_HUMAN; CLEC12A;
CLL-1; DCAL-2; Dendritic cell-associated lectin 2; MICL; Myeloid inhibitory
C-type lectin-like receptor.
研究領(lǐng)域;細胞生物 信號轉(zhuǎn)導(dǎo) 細胞膜受體 細胞粘附分子
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;31kDa
細胞定位;細胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human CLEC12A: 61-160/265
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The C-type lectin/C-type lectin-like domain
(CTL/CTLD) superfamily consists of a variety of proteins that share a common
protein fold and have diverse functions, including cell-cell signaling, cell
adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin
domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a
275 amino acid single-pass type II membrane protein that contains one C-type
lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple
alternatively spliced isoforms that are expressed in neutrophils,
eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell
surface receptor that acts as a negative regulator of granulocyte and
monocyte function and, via this activity, modulates signaling cascades.
CLEC-12A is highly subject to post-translational glycosylation at its
N-terminus and may also exist as a homodimer. Function: Cell surface receptor that modulates signaling
cascades and mediates tyrosine phosphorylation of target MAP kinases. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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