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簡(jiǎn)要描述：甲狀腺受體相關(guān)蛋白CRSP2抗體免 疫 原；KLH conjugated synthetic peptide derived from human CRSP2/MED14: 751-850/1454
產(chǎn)品型號(hào)：GOY-01K0708廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問(wèn) 量：131產(chǎn)品分類
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甲狀腺受體相關(guān)蛋白CRSP2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
甲狀腺受體相關(guān)蛋白CRSP2抗體 | CRSP2 | GOY-01K0708 |
商品屬性：
英文名稱: CRSP2
中文名:甲狀腺受體相關(guān)蛋白CRSP2抗體
別 名；Activator
recruited cofactor 150 kDa component; Activator-recruited cofactor 150 kDa component;
ARC150; Cofactor required for Sp1 transcriptional activation subunit 2; CRSP
complex subunit 2; DRIP150; EXLM1; hRGR1; MED14; MED14_HUMAN; Mediator complex
subunit 14; Mediator of RNA polymerase II transcription subunit 14; RGR1; RGR1
homolog; Thyroid hormone receptor associated protein complex 170 kDa component;
Thyroid hormone receptor-associated protein complex 170 kDa component;
Transcriptional coactivator CRSP150; Trap170; Vitamin D3 receptor interacting
protein complex 150 kDa component; Vitamin D3 receptor-interacting protein
complex 150 kDa component.
研究領(lǐng)域；生長(zhǎng)因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來(lái)源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Monkey, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；161kDa
細(xì)胞定位；細(xì)胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human CRSP2/MED14: 751-850/1454
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The activation of gene transcription is a
multistep process that is triggered by factors that recognize transcriptional
enhancer sites in DNA. These factors work with co-activators to direct
transcriptional initiation by the RNA polymerase II apparatus. The protein
encoded by this gene is a subunit of the CRSP (cofactor required for SP1
activation) complex, which, along with TFIID, is required for efficient
activation by SP1. This protein is also a component of other multisubunit
complexes e.g. thyroid hormone receptor-(TR-) associated proteins which
interact with TR and facilitate TR function on DNA templates in conjunction
with initiation factors and cofactors. This protein contains a bipartite
nuclear localization signal. This gene is known to escape chromosome
X-inactivation. [provided by RefSeq, Jul 2008] Component of the Mediator complex, a coactivator
involved in the regulated transcription of nearly all RNA polymerase
II-dependent genes. Mediator functions as a bridge to convey information from
gene-specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II and the
general transcription factors. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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