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晶狀體蛋白γ1抗體

簡(jiǎn)要描述:晶狀體蛋白γ1抗體免 疫 原;KLH conjugated synthetic peptide derived from human CRYGA: 71-174/174

  • 產(chǎn)品型號(hào):GOY-01K4856
  • 廠商性質(zhì):科研
  • 更新時(shí)間:2023-10-24 00:00:00
  • 訪  問(wèn)  量:152

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詳細(xì)介紹

晶狀體蛋白γ1抗體


產(chǎn)品名稱(chēng)

英文名稱(chēng)

貨號(hào)

晶狀體蛋白γ1抗體

CRYGA

GOY-01K4856

商品屬性:

英文名稱(chēng): CRYGA

中文名:晶狀體蛋白γ1抗體

    名;CRY g A; CRYG1; CRGA_HUMAN; CRYG5; Crystallin, gamma 1; Crystallin, gamma A; Gamma A crystallin; Gamma crystallin 5; Gamma crystallin A;  γA-crystallin; γ A-crystallin.

研究領(lǐng)域;細(xì)胞生物  神經(jīng)生物學(xué)

抗體來(lái)源;Rabbit

克隆類(lèi)型;Polyclonal

交叉反應(yīng);(predicted: Human, Mouse, Rat, Horse, Rabbit, )

產(chǎn)品應(yīng)用;IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理論分子量;21kDa

細(xì)胞定位;細(xì)胞外基質(zhì)

    狀;Liquid

    度;1mg/ml

免 疫 原;KLH conjugated synthetic peptide derived from human CRYGA: 71-174/174

    型;IgG

純化方法;affinity purified by Protein A

緩 沖 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事項(xiàng);This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產(chǎn)品介紹:

Crystallins are separated into two classes: taxon-specific,  or enzyme, and ubiquitous. The latter class constitutes the major proteins of  vertebrate eye lens and maintains the transparency and refractive index of  the lens. Since lens central fiber cells lose their nuclei during  development, these crystallins are made and then retained throughout life,  making them extremely stable proteins. Mammalian lens crystallins are divided  into alpha, beta, and gamma families; beta and gamma crystallins are also  considered as a superfamily. Alpha and beta families are further divided into  acidic and basic groups. Seven protein regions exist in crystallins: four  homologous motifs, a connecting peptide, and N- and C-terminal extensions.  Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins  typically lacking connecting peptides and terminal extensions. They are  differentially regulated after early development. Four gamma-crystallin genes  (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G)  are tandemly organized in a genomic segment as a gene cluster. Whether due to  aging or mutations in specific genes, gamma-crystallins have been involved in  cataract formation. [provided by RefSeq, Jul 2008]

The human gamma-crystallin genes constitute a  multigene family whose members are expressed only in the eye lens.  Crystallins are separated into two classes: taxon-specific, or enzyme, and  ubiquitous. The latter class constitutes the major proteins of vertebrate eye  lens and maintains the transparency and refractive index of the lens. Since  lens central fiber cells lose their nuclei during development, these  crystallins are made and then retained throughout life, making them extremely  stable proteins. Mammalian lens crystallins are divided into alpha, beta, and  gamma families; beta and gamma crystallins are also considered as a  superfamily. Gamma-crystallins are a homogeneous group of highly symmetrical,  monomeric proteins typically lacking connecting peptides and terminal  extensions. They are differentially regulated after early development.  Whether due to aging or mutations in specific genes, gamma-crystallins have  been involved in cataract formation.

 

 

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多克隆抗體制備:

我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。

鼠單克隆抗體制備:

客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專(zhuān)業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。

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重組抗體表達(dá)服務(wù):

重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類(lèi)型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。

單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):

我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。

抗體定制服務(wù):

已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專(zhuān)業(yè)服務(wù),主要面向工業(yè)客戶。

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