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簡要描述：皮膚T細胞淋巴瘤相關(guān)抗原5抗體免 疫 原；KLH conjugated synthetic peptide derived from human CTAGE5: 268-360/804
產(chǎn)品型號：GOY-01K1981廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：148產(chǎn)品分類
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皮膚T細胞淋巴瘤相關(guān)抗原5抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
皮膚T細胞淋巴瘤相關(guān)抗原5抗體 | CTAGE5 | GOY-01K1981 |
商品屬性：
英文名稱: CTAGE5
中文名:皮膚T細胞淋巴瘤相關(guān)抗原5抗體
別 名；cTAGE 5A; cTAGE
5B; cTAGE 5C; cTAGE 5D; cTAGE family member 5; CTAGE family, member 5; cTAGE5A;
cTAGE5B; cTAGE5C; cTAGE5D; CTGE5_HUMAN; Cutaneous T cell lymphoma associated
antigen 5; Cutaneous T-cell lymphoma-associated antigen 5; MEA11; MEA6;
Meningioma expressed antigen 6 (coiled coil proline rich); Meningioma expressed
antigen 6/11; Meningioma-expressed antigen 6/11; MGEA; MGEA11; MGEA6; Protein
cTAGE 5; Protein cTAGE-5.
研究領(lǐng)域；腫瘤 細胞生物 免疫學(xué) 淋巴細胞 t-淋巴細胞 腫瘤細胞生物標(biāo)志物
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；91kDa
細胞定位；細胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human CTAGE5: 268-360/804
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Cutaneous T cell lymphomas (CTCL) represent a
group of malignancies that originate from CD4-T lymphocytes and manifest on
the skin. CTCL is a general term for several neoplasms including mycosis
fungoides, T cell leukemia/ lymphoma and pagetoid reticulosis, all of which
are very difficult to treat in the advanced stages. CTAGE2 (cutaneous T cell
lymphoma associated-antigen 2) is a member of the cancer/testis antigen
family of proteins (CTAGE) that, under normal conditions, are found primarily
in the testis with little or no expression in other parts of the body.
Another member of the CTAG family, namely CTAGE5 (also known as MEA11, MEA6,
MGEA11 or MGEA6), is a tumor associated antigen that is found in tumors of
various origins, including cutaneous T cell lymphomas. Both CTAGE2 and CTAGE5
are expressed as multiple isoforms due to alternative splicing events. Tumor-associated antigen.Tissue
specificity:Isoform 5A is expressed only in testis (at the protein level).
Other isoforms are expressed in several other normal tissues, including
brain, muscle and cranial skin. Isoform 5A (at protein level) and isoform 5B
are expressed in cutaneous T-cell lymphoma (CTCL) cell lines, colorectal
carcinomas, breast carcinomas and melanoma. Isoform 5B, but not isoform 5A,
is expressed in head and neck squamous cell carcinoma. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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