簡要描述:鈣粘蛋白相關(guān)蛋白CTNNA3抗體免 疫 原;KLH conjugated synthetic peptide derived from human CTNNA3: 131-230/895
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鈣粘蛋白相關(guān)蛋白CTNNA3抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
鈣粘蛋白相關(guān)蛋白CTNNA3抗體 | CTNNA3 | GOY-01K4649 |
商品屬性:
英文名稱: CTNNA3
中文名:鈣粘蛋白相關(guān)蛋白CTNNA3抗體
別 名;4930429L08Rik;
4933408A16; Alpha catenin like protein; Alpha T catenin; Alpha T-catenin;
Cadherin associated protein; Cadherin-associated protein; Catenin alpha 3;
Catenin alpha-3; Catna3; CTNA3_HUMAN; CTNNA3; MGC26194; MGC75041;
OTTHUMP00000019684; OTTMUSP00000028119; OTTMUSP00000028120; RP11-433J16.1;
VR22. αT-catenin
研究領(lǐng)域;細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;100kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human CTNNA3: 131-230/895
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The catenins are ubiquitously expressed,
cytoplasmic proteins that associate with E-cadherin at cellular junctions.
Catenin/cadherin complexes play an important role in mediating cellular
adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid
protein that is most abundantally expressed in cardiomyocytes and in the
peritubular myoid cells of the testis. alpha T-catenin binds to alpha
E-catenin as well as to beta-catenin, and it functions to inhibit Wnt
signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on
chromosome 10, and mutations in this gene show a strong correlation to
late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy. May be involved in formation of stretch-resistant
cell-cell adhesion complexes. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進(jìn)行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺,能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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