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簡(jiǎn)要描述：凋亡誘導(dǎo)受體TNFRSF25抗體免 疫 原；KLH conjugated synthetic peptide derived from human TNFRSF25: 25-100/417
產(chǎn)品型號(hào)：GOY-01K2302廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問(wèn) 量：121產(chǎn)品分類(lèi)
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凋亡誘導(dǎo)受體TNFRSF25抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
凋亡誘導(dǎo)受體TNFRSF25抗體 | D3R | GOY-01K2302 |
商品屬性：
英文名稱: D3R
中文名:凋亡誘導(dǎo)受體TNFRSF25抗體
別 名；Apo 3; Apo-3;
Apo3; Apoptosis inducing receptor AIR; Apoptosis inducing receptor; Apoptosis
mediating receptor; Apoptosis mediating receptor DR 3; Apoptosis mediating
receptor DR3; Apoptosis mediating receptor TRAMP; Apoptosis-inducing receptor
AIR; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; DDR
3; DDR3; Death domain receptor 3; Death Receptor 3; Death receptor beta; DR 3; LARD;
Lymphocyte associated receptor of death; Lymphocyte-associated receptor of
death; Protein WSL; Protein WSL-1; TNFRSF 12; TNFRSF 25; TNFRSF12; TNFRSF25;
TNR25_HUMAN; TR 3; TR3; TRAMP; Translocating chain association membrane
protein; Tumor necrosis factor receptor superfamily member 12; Tumor necrosis
factor receptor superfamily member 25; WSL 1; WSL; WSL LR; WSL protein; WSL1;
WSL1 protein; WSLLR.
研究領(lǐng)域；神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來(lái)源；Rabbit
克隆類(lèi)型；Polyclonal
交叉反應(yīng)；Human,
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；43kDa
細(xì)胞定位；細(xì)胞膜 分泌型蛋白
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human TNFRSF25: 25-100/417 <Extracellular>
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The protein encoded by this gene is a member of
theTNF-receptor superfamily. This receptor is expressed preferentiallyin the
tissues enriched in lymphocytes, and it may play a role inregulating
lymphocyte homeostasis. This receptor has been shown tostimulate NF-kappa B
activity and regulate cell apoptosis. Thesignal transduction of this receptor
is mediated by various deathdomain containing adaptor proteins. Knockout
studies in micesuggested the role of this gene in the removal of
self-reactive Tcells in the thymus. Multiple alternatively spliced
transcriptvariants of this gene encoding distinct isoforms have beenreported,
most of which are potentially secreted molecules. Thealternative splicing of
this gene in B and T cells encounters aprogrammed change upon T-cell
activation, which predominantlyproduces full-length, membrane bound isoforms,
and is thought to beinvolved in controlling lymphocyte proliferation induced
by T-cellactivation. [provided by RefSeq, Jul 2008]. Receptor for TNFSF12/APO3L/TWEAK. Interacts
directlywith the adapter TRADD. Mediates activation of NF-kappa-B andinduces
apoptosis. May play a role in regulating lymphocytehomeostasis. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專(zhuān)業(yè)的建議。在制備過(guò)程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類(lèi)型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專(zhuān)業(yè)服務(wù)，主要面向工業(yè)客戶。
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