簡(jiǎn)要描述:癌基因刪去蛋白DICE1抗體免 疫 原;KLH conjugated synthetic peptide derived from human DDX26/DICE1: 1-100/887
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癌基因刪去蛋白DICE1抗體
產(chǎn)品名稱(chēng) | 英文名稱(chēng) | 貨號(hào) |
癌基因刪去蛋白DICE1抗體 | DDX26/DICE1 | GOY-01K0442 |
商品屬性:
英文名稱(chēng): DDX26/DICE1
中文名:癌基因刪去蛋白DICE1抗體
別 名;DBI 1; DBI-1;
DBI1; DDX26; DDX26A; DEAD box protein; DEAD/H (Asp Glu Ala Asp/His) box
polypeptide 26; Deleted in cancer 1; DICE1; DKFZp434B105; HDB; Int6;
INT6_HUMAN; Integrator complex subunit 6; INTS 6; INTS6; Notchl2;
OTTHUMP00000018439; OTTHUMP00000215034; OTTHUMP00000215036; Protein DDX26;
Protein deleted in cancer 1; RNA helicase HDB.
研究領(lǐng)域;腫瘤 細(xì)胞生物 轉(zhuǎn)運(yùn)蛋白 表觀遺傳學(xué)
抗體來(lái)源;Rabbit
克隆類(lèi)型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Pig, Horse, Rabbit, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;100kDa
細(xì)胞定位;細(xì)胞核
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human DDX26/DICE1: 1-100/887
亞 型;IgG
純化方法;affinity purified
by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
DEAD box proteins, characterized by the conserved
motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded
by this gene is a DEAD box protein that is part of a complex that interacts
with the C-terminus of RNA polymerase II and is involved in 3' end processing
of snRNAs. In addition, this gene is a candidate tumor suppressor and located
in the critical region of loss of heterozygosity (LOH). Three transcript
variants encoding two different isoforms have been found for this gene.
[provided by RefSeq, Jul 2008] Component of the Integrator complex, a complex
involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in
their 3'-box-dependent processing. The Integrator complex is associated with
the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and
is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role;
an ectopic expression suppressing tumor cell growth. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專(zhuān)業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類(lèi)型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專(zhuān)業(yè)服務(wù),主要面向工業(yè)客戶。
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