歡迎來(lái)到上海谷研實(shí)業(yè)有限公司網(wǎng)站！
咨詢電話：18321818584歡迎來(lái)到上海谷研實(shí)業(yè)有限公司網(wǎng)站！咨詢電話：18321818584
簡(jiǎn)要描述：表皮乳頭源性蛋白6抗體免 疫 原；KLH conjugated synthetic peptide derived from human DERP6/C17orf81: 221-316/316
產(chǎn)品型號(hào)：GOY-01K2247廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：131產(chǎn)品分類
Product Category相關(guān)文章
Related Articles詳細(xì)介紹
表皮乳頭源性蛋白6抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
表皮乳頭源性蛋白6抗體 | DERP6 | GOY-01K2247 |
商品屬性：
英文名稱: DERP6
中文名:表皮乳頭源性蛋白6抗體
別 名；MST071; MSTP071;
chromosome 17 open reading frame 81; Dermal papilla derived protein 6; dermal
papilla-derived protein 6; DERP6; HSPC002; S phase 2 protein; ELP5_HUMAN.
研究領(lǐng)域；腫瘤 細(xì)胞生物 表觀遺傳學(xué)
抗體來(lái)源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal dilutions/concentrations
should be determined by the end user.
理論分子量；35kDa
細(xì)胞定位；細(xì)胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human DERP6/C17orf81: 221-316/316
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M TBS(pH7.4)
with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
DERP6, is a 316 amino acid protein that localizes
to the cytoplasm and exists as multiple alternatively spliced isoforms.
Expressed ubiquitously with highest expression in liver, heart, testis, brain
and skeletal muscle, DERP6 is thought to be involved in p53-mediated
transcriptional regulation. The gene encoding DERP6 maps to human chromosome
17, which comprises over 2.5% of the human genome and encodes over 1,200
genes. Two key tumor suppressor genes are associated with chromosome 17,
namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular
genetic integrity by moderating cell fate through DNA repair versus cell
death. Malfunction or loss of p53 expression is associated with malignant
cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in
DNA repair, though specifically it is recognized as a genetic determinant of
early onset breast cancer and predisposition to cancers of the ovary, colon,
prostate gland and fallopian tubes. Acts as subunit of the RNA polymerase II elongator
complex, which is a histone acetyltransferase component of the RNA polymerase
II (Pol II) holoenzyme and is involved in transcriptional elongation.
Elongator may play a role in chromatin remodeling and is involved in
acetylation of histones H3 and probably H4. Involved in cell migration (By similarity).
May be involved in TP53-mediated transcriptional regulation. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
產(chǎn)品咨詢
聯(lián)系人：銷售部
地址：上海市嘉定區(qū)澄瀏公路52號(hào)盛創(chuàng)企業(yè)
郵箱：[email protected]
手機(jī)：18321818584 / 15026555973歡迎您關(guān)注我們的微信了解更多信息
掃一掃電話
微信掃一掃