簡(jiǎn)要描述:DNA聚合酶β抗體免 疫 原;Recombinant human DNA Polymerase beta protein: 1-335/335
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DNA聚合酶β抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
DNA聚合酶β抗體 | DNA Polymerase beta | GOY-01K1021 |
商品屬性:
英文名稱: DNA Polymerase beta
中文名:DNA聚合酶β抗體
別 名;DNA Polymerase
beta; DNA pol beta; DNA directed DNA polymerase beta; DNA polymerase beta; DNA
polymerase beta subunit; DPOLB_HUMAN; MGC125976; Pol B; Pol beta; PolB;
Polymerase (DNA directed) beta.
研究領(lǐng)域;細(xì)胞生物 染色質(zhì)和核信號(hào) 表觀遺傳學(xué)
抗體來(lái)源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);Human,
Mouse,
產(chǎn)品應(yīng)用;WB=1:200-1000
IHC-P=1:100-500 IF=1:20-200 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;37kDa
細(xì)胞定位;細(xì)胞核
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;Recombinant
human DNA Polymerase beta protein: 1-335/335
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
DNA replication, recombination and repair, all of
which are necessary for genomic stability, require the presence of
exonucleases (1). In DNA replication, these enzymes are involved in the
processing of Okazaki fragments, whereas in DNA repair, they function to
excise damaged DNA fragments and correct recombinational mismatches (2).
These exonucleases include the family of DNA polymerases (3). DNA pol α, β, ?, and e are involved in DNA replication and repair (4). DNA pol ? and DNA pol e are multisubunit enzymes, with DNA pol ? consisting of two subunits p125, which interacts with the sliding
DNA clamp protein PCNA, and p50 (5). The nuclear-encoded DNA pol ? is the
only DNA polymerase required for the replication of the mitochondrial DNA
(6). DNA pol Ω is ubiquitously expressed in various
tissues and mediates the cellular mechanism of damage-induced mutagenesis
(7). DNA pol ? is a DNA polymerase-helicase that
binds ATP and is involved in the repair of interstrand crosslinks (8). |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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