簡要描述:紅細(xì)胞分化相關(guān)因子1抗體免 疫 原;KLH conjugated synthetic peptide derived from Human EDRF1/C10orf137: 101-200/1238
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紅細(xì)胞分化相關(guān)因子1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
紅細(xì)胞分化相關(guān)因子1抗體 | EDRF1 | GOY-01K2230 |
商品屬性:
英文名稱: EDRF1
中文名:紅細(xì)胞分化相關(guān)因子1抗體
別 名;C10orf137
protein; Chromosome 10 open reading frame 137; EDRF1; Erythroid differentiation
related factor 1; EDRF1_HUMAN.
研究領(lǐng)域;細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 干細(xì)胞 細(xì)胞周期蛋白 細(xì)胞分化 表觀遺傳學(xué)
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;139kDa
細(xì)胞定位;細(xì)胞核
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from Human EDRF1/C10orf137: 101-200/1238
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The tetratricopeptide repeat (TPR) motif is a
degenerate, 34 amino acid sequence found in many proteins and acts to mediate
protein-protein interactions in various pathways. At the sequence level,
there can be up to 16 tandem TPR repeats, each of which has a
helix-turn-helix shape that stacks on other TPR repeats to achieve ligand
binding specificity. EDRF1 (erythroid differentiation-related factor 1), also
known as C10orf137 (chromosome 10 open reading frame 137), is a 1,238 amino
acid protein containing two TPR repeats. Localizing to nucleus, EDRF1 is
involved in transcriptional activation of globin genes by regulating
DNA-binding activity of GATA-1 transcription factor. EDRF1 may also play an
important role in organ development and histological differentiation. EDRF1
exists as four alternatively spliced isoforms and is encoded by a gene
mapping to human chromosome 10q26.13. Transcription factor involved in erythroid
differentiation. Involved in transcriptional activation of the globin gene. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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