簡要描述:胚胎外精子同源蛋白1抗體免 疫 原;KLH conjugated synthetic peptide derived from human ESX1: 21-120/406
產(chǎn)品分類
Product Category相關(guān)文章
Related Articles詳細介紹
胚胎外精子同源蛋白1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
胚胎外精子同源蛋白1抗體 | ESX1 | GOY-01K4806 |
商品屬性:
英文名稱: ESX1
中文名:胚胎外精子同源蛋白1抗體
別 名;Epx; ESX1;
ESX1_HUMAN; ESX1L; ESXR1; Etx; Extraembryonic; Extraembryonic spermatogenesis
homeobox 1; homeobox 1; Homeobox protein ESX1-C; spermatogenesis; Spx1.
研究領(lǐng)域;細胞生物 免疫學 發(fā)育生物學 信號轉(zhuǎn)導 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應;(predicted:
Human, )
產(chǎn)品應用;IHC-P=1:100-500
IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in
other applications.
optimal dilutions/concentrations
should be determined by the end user.
理論分子量;44kDa
細胞定位;細胞核 細胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human ESX1: 21-120/406
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene encodes a dual-function 65 kDa protein
that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment
with a paired-like homeodomain and a 20 kDa C-terminal fragment with a
proline-rich domain. The C-terminal fragment localizes to the cytoplasm while
the N-terminal fragment localizes exclusively to the nucleus. In contrast to
human, the mouse homolog has a novel PN/PF motif in the C-terminus and is
paternally imprinted in placental tissue. This gene likely plays a role in
placental development and spermatogenesis. [provided by RefSeq, Jan 2010] May coordinately regulate cell cycle progression
and transcription during spermatogenesis. Inhibits degradation of
polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle
at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the
sequence 5'-TAATGTTATTA-3' which is present within the first intron of the
KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit
cyclin turnover. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應用驗證需求。技術(shù)服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務,包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務,如動物免疫、動物飼養(yǎng)、抗體修飾服務(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務。
抗體定制服務:
已注冊商標,主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務,主要面向工業(yè)客戶。
產(chǎn)品咨詢
歡迎您關(guān)注我們的微信了解更多信息
電話
微信掃一掃