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簡要描述：補(bǔ)體因子I輕鏈抗體免 疫 原；KLH conjugated synthetic peptide derived from mouse Factor I light chain : 451-550/582
產(chǎn)品型號：GOY-01K0139廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：136產(chǎn)品分類
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補(bǔ)體因子I輕鏈抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
補(bǔ)體因子I輕鏈抗體 | Factor I light chain | GOY-01K0139 |
商品屬性：
英文名稱: Factor I light chain
中文名:補(bǔ)體因子I輕鏈抗體
別 名；AHUS3; ARMD13; C3b INA; C3b inactivator; C3B/C4B inactivator;
C3BINA; CFAI_HUMAN; Cfi; Complement component I; Complement control protein
factor I; Complement factor I; Complement factor I heavy chain; Complement
factor I light chain; F1; factor I; FactorI; FI; I factor; IF; KAF;
Konglutinogen activating factor; Light chain of factor I; OTTHUMP00000219728;
OTTHUMP00000221928
研究領(lǐng)域；心血管 免疫學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)； Rat, (predicted: Mouse, Cow, )
產(chǎn)品應(yīng)用；IHC-P=1:100-500（石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；22kDa
細(xì)胞定位；細(xì)胞外基質(zhì) 分泌型蛋白
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from mouse Factor I light chain :
451-550/582
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The complement pathway is an important host
defense system that contributes to both innate and acquired immunity. There
are three pathways of complement activation: the classical pathway, lectin
pathway and alternative pathway. Complement protein Factor I is a key serine
protease that modulates the complement cascade by regulating the levels of C3
convertases. It circulates in plasma as a heavily N-glycosylated heterodimer
made up of two disulfide linked chains, each carrying three N-linked
oligosaccharide chains that may have both structural and functional roles in
the interactions with the natural substrate and the cofactor during
catalysis. Factor I is a serine protease with a high degree of specificity
for C3b and C4b. It requires protein cofactors for cleavage of these
complement proteins; Factor H, CR1 or MCP are required for C3b cleavage, and
C4bp or CR1 are required for C4b cleavage. Responsible for cleaving the alpha-chains of C4b
and C3b in the presence of the cofactors C4-binding protein and factor H
respectively. Subcellular Location : Secreted; extracellular space. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報價，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報價，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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