簡要描述:FAM162A蛋白抗體免 疫 原;KLH conjugated synthetic peptide derived from human FAM162A: 1-100/154
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FAM162A蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
FAM162A蛋白抗體 | FAM162A | GOY-01K2513 |
商品屬性:
英文名稱: FAM162A
中文名:FAM162A蛋白抗體
別 名;C3orf28;
Chromosome 3 open reading frame 28; DC16; E2-induced gene 5 protein; E2IG5;
F162A_HUMAN; Fam162a; Family with sequence similarity 162, member A1; Growth
and transformation-dependent protein; HGTD P; HIF-1 alpha-responsive
proapoptotic molecule; OTTHUMP00000215578; OTTHUMP00000215579;
OTTHUMP00000215580; Protein FAM162A.
研究領(lǐng)域;細胞生物 免疫學(xué)
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Pig, Horse, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;17kDa
細胞定位;細胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human FAM162A: 1-100/154
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
HGTD-P (human growth and transformation-dependent
protein), also known as E2IG5 or FAM162A, is a 154 amino acid single-pass
membrane protein belonging to the UPF0389 family. Considered a proapoptotic
protein, HGTD-P is an effector of cell death induced by hypoxia-ischemia (HI)
and is therefore considered a potential target in treating HI-induced brain
damage. HGTD-P localizes to the mitochondria and, when overexpressed, induces
the mitochondrial permeability transition by interacting with voltage
dependent anion channels. HGTD-P facilitates apoptotic cell death via the
mitochondrial apoptotic cascades, including permeability transition,
cytochrome c release and caspase 9 activation. HGTD-P is regulated and
activated by HIF-1?through a hypoxia-responsive element on the HGTD-P
promoter region. Subcellular Location: Membrane. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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