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簡要描述：F-box蛋白家族FBXO7抗體免 疫 原；KLH conjugated synthetic peptide derived from human FBXO7: 251-350/522
產(chǎn)品型號：GOY-01K4162廠商性質：科研更新時間：2023-10-24 00:00:00訪 問 量：130產(chǎn)品分類
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F-box蛋白家族FBXO7抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
F-box蛋白家族FBXO7抗體 | FBXO7 | GOY-01K4162 |
商品屬性：
英文名稱: FBXO7
中文名:F-box蛋白家族FBXO7抗體
別 名；F box only
protein 7; F box protein 7; F-box protein 7; FBX; FBX07; FBX7; PARK15; PKPS;
研究領域；細胞生物 免疫學 細胞周期蛋白 表觀遺傳學 泛素
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；(predicted:
Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, )
產(chǎn)品應用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；59kDa
細胞定位；細胞核 細胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human FBXO7: 251-350/522
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
FBXO7, also known as FBX, FBX7 or PKPS, is a 522
amino acid protein that contains one F-box domain and functions as a
component of the SCF complex. Defects in the gene encoding FBXO7 are
associated with parkinsonian-pyramidal syndrome (PKPS), a hypokinetic rigid
disorder that exhibits Parkinsonian and pyramidal-associated symptoms.The
FBXO7 gene encodes a member of the F-box protein family which is
characterized by an approximately 40 amino acid motif, the F-box. F-box
proteins constitute one of the four subunits of the ubiquitin protein ligase
complex called SCFs (SKP1-cullin-F-box), which function in
phosphorylation-dependent ubiquitination. The F-box proteins are divided into
3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich
repeats, and Fbxs containing either different protein-protein interaction
modules or no recognizable motifs. The protein encoded by this gene belongs
to the Fbxs class and it may play a role in regulation of hematopoiesis.
Alternatively spliced transcript variants of this gene have been identified
with the full-length natures of only some variants being determined. Function: Substrate recognition component of a
(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates
the ubiquitination and subsequent proteasomal degradation of target proteins.
Recognizes BIRC2 and DLGAP5. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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