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簡要描述:G蛋白偶聯(lián)受體41抗體免 疫 原;KLH conjugated synthetic peptide derived from human FFAR3: 121-220/346
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G蛋白偶聯(lián)受體41抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
G蛋白偶聯(lián)受體41抗體 | FFAR3/GPR41 | GOY-01K0737 |
商品屬性:
英文名稱: FFAR3/GPR41
中文名:G蛋白偶聯(lián)受體41抗體
別 名;FFA3R; Ffar3;
FFAR3_HUMAN; Free fatty acid receptor 3; G protein coupled receptor 41;
G-protein coupled receptor 41; gpcr41; GPR41; gpr42.
研究領(lǐng)域;細(xì)胞生物 免疫學(xué) 結(jié)合蛋白 G蛋白偶聯(lián)受體 細(xì)胞骨架 G蛋白信號
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;39kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human FFAR3: 121-220/346
<Extracellular>
亞 型;IgG
純化方法;affinity purified
by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
G protein-coupled receptors (GPRs), also known as
seven transmembrane receptors, heptahelical receptors or 7TM receptors,
comprise a superfamily of proteins that play a role in many different
stimulus-response pathways. GPRs translate extracellular signals into
intracellular signals (a process called G-protein activation) and they
respond to a variety of signaling molecules, such as hormones and
neurotransmitters. GPR41 (G-protein coupled receptor 41), also known as FFAR3
(Free fatty acid receptor 3), is a 346 amino acid multi-pass membrane protein
that belongs to the G protein-coupled receptor family. Expressed at high
levels in adipose tissue and at lower levels throughout the body, GPR41
functions as a receptor for short chain fatty acids via elevation of
intracellular calcium levels and inhibition of adenylyl cyclase. Function: Receptor for short chain fatty acids. The activity
of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate,
intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of
intracellular cAMP accumulation. Coupled exclusively to the pertussis
toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists
of this receptor is propionate = pentanoate = butyrate > acetate >
formate. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報價,按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報價,按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺,能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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