簡要描述:成纖維細(xì)胞生長因子受體5抗體免 疫 原;KLH conjugated synthetic peptide derived from human FGFR5/FGFRL1: 231-330/504
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成纖維細(xì)胞生長因子受體5抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
成纖維細(xì)胞生長因子受體5抗體 | FGFR5 | GOY-01K0939 |
商品屬性:
英文名稱: FGFR5
中文名:成纖維細(xì)胞生長因子受體5抗體
別 名;FGF homologous
factor receptor; FGF receptor like protein 1; FGFR 5; FGFR like protein; FGFR5;
FGFRL1; FHFR; Fibroblast growth factor receptor 5; Fibroblast growth factor
receptor like 1; FGRL1_HUMAN.
研究領(lǐng)域;細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 生長因子和激素
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;52kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human FGFR5/FGFRL1: 231-330/504
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
FGFRL1 is a member of the fibroblast growth factor
receptor (FGFR) family, where amino acid sequence is highly conserved between
members and throughout evolution. FGFR family members differ from one another
in their ligand affinities and tissue distribution. A full-length
representative protein would consist of an extracellular region, composed of
three immunoglobulin-like domains, a single hydrophobic membrane-spanning
segment and a cytoplasmic tyrosine kinase domain. The extracellular portion
of the protein interacts with fibroblast growth factors, setting in motion a
cascade of downstream signals, ultimately influencing mitogenesis and
differentiation. A marked difference between FGFRL1 and the other family
members is its lack of a cytoplasmic tyrosine kinase domain. The result is a
transmembrane receptor that could interact with other family members and
potentially inhibit signaling. Multiple alternatively spliced transcript
variants encoding the same isoform have been found. UniProtKB/Swiss-Prot: Q8N441.1 FASTA Graphics Go
to: LOCUS FGRL1_HUMAN 504 aa linear PRI 01-MAY-2013 DEFINITION RecName:
Full=Fibroblast growth factor receptor-like 1; Short=FGF receptor-like
protein 1; AltName: Full=FGF homologous factor receptor; AltName:
Full=FGFR-like protein; AltName: Full=Fibroblast growth factor receptor 5;
Short=FGFR-5; Flags: Precursor. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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