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簡要描述：FLYWCH1蛋白抗體免 疫 原；KLH conjugated synthetic peptide derived from human FLYWCH1: 631-715/715
產(chǎn)品型號：GOY-01K4964廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：132產(chǎn)品分類
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FLYWCH1蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
FLYWCH1蛋白抗體 | FLYWCH1 | GOY-01K4964 |
商品屬性：
英文名稱: FLYWCH1
中文名:FLYWCH1蛋白抗體
別 名；DKFZp761A132;
FWCH1_HUMAN; FLYWCH type zinc finger containing protein 1; FLYWCH zinc finger
1; FLYWCH-type zinc finger 1; KIAA1552.
研究領(lǐng)域；細(xì)胞生物 免疫學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, )
產(chǎn)品應(yīng)用；IHC-P=1:100-500
IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；90kDa
細(xì)胞定位；細(xì)胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human FLYWCH1: 631-715/715
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
FLYWCH1 (FLYWCH-type zinc finger 1) is a 716 amino
acid nuclear protein containing five FLYWCH-type zinc fingers. Existing as
five alternatively spliced isoforms, FLYWCH1 is encoded by a gene located on
human chromosome 16p13.3. Chromosome 16 encodes over 900 genes and comprises
nearly 3% of human cellular DNA. The GAN gene is located on chromosome 16
and, with mutation, may lead to giant axonal neuropathy, a nervous system
disorder characterized by increasing malfunction with growth. The rare
disorder Rubinstein-Taybi syndrome is also associated with chromosome 16
through the CREBBP gene, which encodes a critical CREB binding protein.
Crohn's disease is a gastrointestinal inflammatory condition associated with
chromosome 16 through the NOD2 gene. An association with systemic lupus
erythematosis and a number of other autoimmune disorders with the
pericentromeric region of chromosome 16 has led to the identification of
SLC5A11 as a potential autoimmune modifier. Function: FLYWCH, also commonly known as FLYWCH-type zinc
finger 1, is a nuclear DNA-binding protein. It contains 5 FLYWCH-type zinc
finger domains and is 716 amino acids in length. There are five isoforms of
the protein produced by alternative splicing. Isoform 1 (80 kDa) is the
canonical form. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進(jìn)行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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