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簡(jiǎn)要描述：Ⅲ型纖維連接蛋白域蛋白3A抗體免 疫 原；KLH conjugated synthetic peptide derived from human FNDC3A: 501-600/1198
產(chǎn)品型號(hào)：GOY-01K2371廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問(wèn) 量：130產(chǎn)品分類
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Ⅲ型纖維連接蛋白域蛋白3A抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
Ⅲ型纖維連接蛋白域蛋白3A抗體 | FNDC3A | GOY-01K2371 |
商品屬性：
英文名稱: FNDC3A
中文名:Ⅲ型纖維連接蛋白域蛋白3A抗體
別 名；Fibronectin type
III domain containing protein 3a; FNDC3; HUGO; KIAA0970; FND3A_HUMAN.
研究領(lǐng)域；細(xì)胞生物 發(fā)育生物學(xué) 細(xì)胞粘附分子
抗體來(lái)源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；125kDa
細(xì)胞定位；細(xì)胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human FNDC3A: 501-600/1198
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
FNDC3A is a 1,134 amino acid protein that belongs
to the FNDC3 family of proteins. FNDC3A contains an N-terminal proline-rich
region, nine fibronectin type-III domains (none of which contain an RGD
sequence) and a hydrophobic C-terminal transmembranous helix. Expressed in a
wide variety of tissues, FNDC3A localizes to Golgi vesicles and to the
developing acrosome of spermatids. FNDC3A is believed to function in glycosaminoglycan
and collagen synthesis. In mice, a mutation in the gene encoding FNDC3A
causes male sterility due to defective adhesion between Sertoli cells and
spermatids in the seminiferous epithelium. This suggests that FNDC3A plays an
important role in spermatogenesis, possibly mediating or maintaining the
adhesion between Sertoli cells and spermatids. Function: FNDC3A is a member of a three-gene family in mice.
It is expressed in several tissues including testis, and encodes a novel
protein composed of a proline-rich amino-terminus, nine fibronectin type-III
domains, and a hydrophobic carboxy-terminus. The proline-rich region of each
family member contains conserved amino acids that include a PPGY consensus
binding site for type I WW domain containing proteins. The hydrophobic
carboxy-terminus is similar to that found in 'tail-anchored' proteins,
integral membrane proteins that are localized to the cytosolic face of the
endoplasmic reticulum. Immunohistochemical staining has shown that FNDC3A
localizes to the acrosome of spermatids, as well as to Leydig cells in the
mouse testis. FNDC3A may be involved in mediating spermatid-Sertoli adhesion
during mouse spermatogenesis and mutation of FNDC3A is the cause of male
sterility in sys mice. FNDC3A has also been found to be overexpressed in
human odontoblasts. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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