簡要描述:Ⅲ型纖維連接蛋白域蛋白3B抗體免 疫 原;KLH conjugated synthetic peptide derived from human FNDC3B: 921-1020/1204
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Ⅲ型纖維連接蛋白域蛋白3B抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
Ⅲ型纖維連接蛋白域蛋白3B抗體 | FNDC3B | GOY-01K0973 |
商品屬性:
英文名稱: FNDC3B
中文名:Ⅲ型纖維連接蛋白域蛋白3B抗體
別 名;Factor for
adipocyte differentiation 104; FAD104; fibronectin type III domain containing
3B; FLJ23399; HCV NS5A binding protein 37; NS5ABP37; YVTM2421; MGC10002;
PRO4979; DKFZp686D14170; DKFZp762K137; FND3B_HUMAN.
研究領(lǐng)域;腫瘤 細胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 干細胞
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;133kDa
細胞定位;細胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human FNDC3B: 921-1020/1204
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項;This product
as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Adipogenesis, the process of transforming
pre-adipocytes into mature fat cells, is of particular interest due to the
role adipocytes play in obesity and type II diabetes. Adipocytes have been
shown to affect a variety of functions, including hemostasis, angiogenesis
and energy balance, by secreting hormones and bioactive peptides. The FNDC3B
protein, also designated FAD104 (factor for adipocyte differentiation 104) or
HCV NS5A-binding protein 37, is expressed during early adipogenesis.
Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid
protein that contains nine fibronectin type-III domains. FNDC3B-deficient
mice die within one day of birth, suggesting that FNDC3B is crucial for
postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B
function displayed a reduction in stress fiber formation, indicating a role
for FNDC3B in cell proliferation, adhesion, spreading and migration. Function: May be a positive regulator of adipogenesis. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標,主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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