簡(jiǎn)要描述:多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶1抗體免 疫 原;KLH conjugated synthetic peptide derived from human GALNT1/GalNAc-T1: 101-200/559
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多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶1抗體 | GALNT1 | GOY-01K4498 |
商品屬性:
英文名稱: GALNT1
中文名:多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶1抗體
別 名;GALNAC T1; GalNAc
transferase 1; GalNAc-T1; GALNT 1; GALNT1; GALT1_HUMAN; Polypeptide GalNAc
transferase 1; Polypeptide N acetylgalactosaminyltransferase 1; Polypeptide
N-acetylgalactosaminyltransferase 1 soluble form; pp GaNTase 1; pp-GaNTase 1;
Protein UDP acetylgalactosaminyltransferase 1; Protein-UDP
acetylgalactosaminyltransferase 1; UDP GalNAc:polypeptide N
acetylgalactosaminyltransferase 1; UDP N acetyl alpha D
galactosamine:polypeptide N acetylgalactosaminyltransferase 1 (GalNAc T1); UDP
N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1;
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1.
研究領(lǐng)域;細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo)
抗體來(lái)源;Rabbit
克隆類(lèi)型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;64kDa
細(xì)胞定位;細(xì)胞漿 細(xì)胞膜 分泌型蛋白
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human GALNT1/GalNAc-T1: 101-200/559
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The UDP-N-acetyl-alpha-D-galactosamine:polypeptide
N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are
substrate-specific proteins that catalyze the transfer of GalNAc
(N-acetylgalactosamine) to serine and threonine residues onto various
proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi
apparatus. GalNAc-T1, also known as GALNT1 (Polypeptide
N-acetylgalactosaminyltransferase 1), is a ubiquitously expressed 559 amino
acid single-pass type II membrane protein that localizes to the Golgi
apparatus and, like other GalNAc-Ts, contains a stem region and a C-terminal
ricin/lectin-like domain. GalNAc-T1 catalyzes the first reaction in O-linked
oligosaccharide biosynthesis, namely the transfer of an
N-acetyl-D-galactosamine residue to a protein acceptor. GalNAc-T1 uses
calcium and manganese as cofactors. Due to alternative splicing events, two
GalNAc-T1 isoforms are expressed. Catalyzes the initial reaction in O-linked
oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine
residue to a serine or threonine residue on the protein receptor. Has a broad
spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and
Muc7. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類(lèi)型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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