簡要描述:甘氨酰胺核苷酸合成酶重組兔單克隆抗體免 疫 原;Recombinant Human GART protein : 570-750/1010
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甘氨酰胺核苷酸合成酶重組兔單克隆抗體
產品名稱 | 英文名稱 | 貨號 |
甘氨酰胺核苷酸合成酶重組兔單克隆抗體 | GART | GOY-01K1213 |
商品屬性:
英文名稱: GART
中文名:甘氨酰胺核苷酸合成酶重組兔單克隆抗體
別 名;5'-phosphoribosylglycinamide
transformylase; AIR synthase; AIRS; GAR transformylase; GARS; GARTF;
Glycinamide ribonucleotide synthetase; MGC47764; PAIS; PGFT;
Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylglycinamide
formyltransferase; Phosphoribosylglycinamide formyltransferase
phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase;
Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29;
Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide
synthetase, phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide
synthetase; PRGS; PUR2_HUMAN; Trifunctional purine biosynthetic protein
adenosine 3.
研究領域;腫瘤 細胞生物 信號轉導 新陳代謝 表觀遺傳學
抗體來源;Rabbit
克隆類型;Monoclonal
交叉反應;(predicted:
Human, Mouse, Rat, )
產品應用;WB=1:500
IHC-P=1:100-500 ICC=1:50-200 (石蠟切片需做抗原修復)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;107kDa
細胞定位;細胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;Recombinant
Human GART protein : 570-750/1010
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產品介紹:
Purines are critical for energy metabolism, cell
signaling and cell reproduction and also function as precursors for
coenzymes, energy transfer molecules, regulatory factors and proteins
involved in RNA and DNA synthesis. GART (GAR transformylase), also referred
to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length
and is a key folate-dependent trifunctional enzyme with
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide
synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity
required for de novo purine biosynthesis. Cancer cells require considerable
amounts of purines to sustain their accelerated growth and GART is,
therefore, a target for cancer chemotherapy. GART is highly conserved in
vertebrates. Two isoforms of GART are expressed due to alternative splicing
events. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結果是陽性。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務,包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務,如動物免疫、動物飼養(yǎng)、抗體修飾服務(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務。
抗體定制服務:
已注冊商標,主要用于抗體藥物發(fā)現和開發(fā),是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務,主要面向工業(yè)客戶。
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