簡(jiǎn)要描述:葡萄糖苷酶2β/Glucosidase IIβ抗體免 疫 原;KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta: 101-200/528
產(chǎn)品分類
Product Category相關(guān)文章
Related Articles詳細(xì)介紹
葡萄糖苷酶2β/Glucosidase IIβ抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
葡萄糖苷酶2β/Glucosidase
IIβ抗體 | Glucosidase 2 subunit beta | GOY-01K2383 |
商品屬性:
英文名稱: Glucosidase 2 subunit beta
中文名:葡萄糖苷酶2β/Glucosidase IIβ抗體
別 名;80K-H protein;
AGE-binding receptor 2; AGE-R2; G19P1; GLU2B_HUMAN; Glucosidase 2 subunit beta;
Glucosidase II beta subunit; Glucosidase II subunit beta; Hepatocystin; PCLD;
PKCSH; PLD1; PRKCSH; Protein kinase C substrate 60.1 kDa protein heavy chain;
Protein kinase C substrate 80 Kda protein; Protein kinase C substrate 80K-H;
Protein kinase C substrate, 80 Kda protein.
研究領(lǐng)域;腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;58kDa
細(xì)胞定位;細(xì)胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human Glucosidase 2 subunit beta:
101-200/528
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Trimming of glucoses from N-linked core glycans on
newly synthesized glycoproteins occurs sequentially through the action of Glucosidases
I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized
enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb)
which form a defined heterodimeric complex. Glucosidase IIa is the catalyitc
core of the enzyme and can function independently of the b subunit. The
sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic
acid with a putative ER retention signal (HDEL) at the C-terminus. The
phosphorylated form of Glucosidase IIb is localized in the plasma membrane
and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma
cells. Glucosidase IIb was first purified from a human carcinoma cell line as
a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus,
Glucosidase IIb retains the complete complex in the ER. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
產(chǎn)品咨詢
歡迎您關(guān)注我們的微信了解更多信息
電話
微信掃一掃