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簡要描述：5’-三磷酸聚核苷酸抗體免 疫 原；KLH conjugated synthetic peptide derived from human HCE: 451-550/597
產(chǎn)品型號：GOY-01K1195廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：136產(chǎn)品分類
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5’-三磷酸聚核苷酸抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
5’-三磷酸聚核苷酸抗體 | HCE | GOY-01K1195 |
商品屬性：
英文名稱: HCE
中文名:5’-三磷酸聚核苷酸抗體
別 名；RNGTT; CAP1A;
GTase; GTP--RNA guanylyltransferase; hCAP; HCAP1; HcE; HCE1; MCE1; MCE1_HUMAN;
mRNA 5''-triphosphatase; mRNA capping enzyme; mRNA guanyltransferase; mRNA
guanylyltransferase; polynucleotide 5' trisphosphatase; RNA guanylyltransferase
and 5' phosphatase; TPase;
研究領(lǐng)域；細胞生物 免疫學(xué) 染色質(zhì)和核信號 表觀遺傳學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；69kDa
細胞定位；細胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human HCE: 451-550/597
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
RNGTT (RNA guanylyltransferase and 5'-phosphatase)
is a 597 amino acid protein that localizes to the nucleus and exists as four
alternatively spliced isoforms. Expressed in kidney, lung, heart, brain,
liver, testis, skin and muscle, RNGTT acts as a bifunctional mRNA-capping
enzyme that exhibits RNA 5'-triphosphatase activity at its N-terminus and
mRNA guanylyltransferase activity at its C-terminus. Via its catalytic
activity, RNGTT facilitates the first two steps of mRNA cap formation, naming
the removal of a γ-phosphate
from the end of nascent mRNA and the subsequent transfer of the phospho
residue to the 5’-diphosphate terminus. The gene
encoding RNGTT maps to human chromosome 6, which contains 170 million base
pairs and comprises nearly 6% of the human genome. Function: Bifunctional mRNA-capping enzyme exhibiting RNA
5'-triphosphatase activity in the N-terminal part and mRNA
guanylyltransferase activity in the C-terminal part. Catalyzes the first two
steps of cap formation: by removing the gamma-phosphate from the
5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by
transferring the gmp moiety of GTP to the 5'-diphosphate terminus. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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