歡迎來(lái)到上海谷研實(shí)業(yè)有限公司網(wǎng)站！
咨詢電話：18321818584歡迎來(lái)到上海谷研實(shí)業(yè)有限公司網(wǎng)站！咨詢電話：18321818584
簡(jiǎn)要描述：紫外切除修復(fù)蛋白R(shí)AD23A抗體注意事項(xiàng)；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品型號(hào)：GOY-01K2423廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問(wèn) 量：165產(chǎn)品分類
Product Category相關(guān)文章
Related Articles詳細(xì)介紹
紫外切除修復(fù)蛋白R(shí)AD23A抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
紫外切除修復(fù)蛋白RAD23A抗體 | hHR23A | GOY-01K2423 |
商品屬性：
英文名稱: hHR23A
中文名:紫外切除修復(fù)蛋白RAD23A抗體
別 名；hHR 23A; HR23A;
R23A; MGC111083; RAD 23a; RAD23 homolog A; RAD23 yeast homolog A; RAD23a;
RD23A_HUMAN; UV excision repair protein RAD23; UV excision repair protein RAD23
homolog A.
研究領(lǐng)域；細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 表觀遺傳學(xué)
抗體來(lái)源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal dilutions/concentrations
should be determined by the end user.
理論分子量；40kDa
細(xì)胞定位；細(xì)胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human hHR23A: 281-363/363
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Mammalian cells express two Rad23 (genome repair
protein) homologs, Rad23A (also designated HR23A) and Rad23B (also designated
HR23B). In typical cells, mouse Rad23B is approximately ten times more
abundant than mouse Rad23A. Endogenous XPC (xeroderma pigmentosum C protein)
located in wildtype mouse embryonic fibroblasts is relatively stable; its
steady-state level and stability appear to be significantly reduced by a
targeted interruption of the mouse Rad23B gene, but not by that of mouse Rad23A.
Loss of both mouse Rad23 genes causes a strong further reduction of the XPC
protein level. The RAD23 genes (RAD23A and RAD23B), which encode the human
Rad23 proteins, are crucial for excision-repair of UV-damaged DNA. RAD23
genes resemble the other DNA repair genes, RAD2, RAD6, RAD7, RAD18 and RAD54,
all of which also exhibit increased transcription in response to DNA damage
and during meiosis. Rad23 is a nuclear protein containing an ubiquitin-like
domain required for biological functions. The protein, which is highly
conserved, is involved in nucleotide excision repair (NER) that associates
with the proteasome via its N-terminus. The C-terminal ubiquitin-associated
domain of Rad23 is evolutionarily conserved from yeast to humans. Rad23 may
also act as a regulator for the activity of the 26S Proteasome Function: Multiubiquitin chain receptor involved in
modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin
chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked
polyubiquitin chains. Proposed to be capable to bind simultaneously to the
26S proteasome and to polyubiquitinated substrates and to deliver
ubiquitinated proteins to the proteasome. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
產(chǎn)品咨詢
聯(lián)系人：銷售部
地址：上海市嘉定區(qū)澄瀏公路52號(hào)盛創(chuàng)企業(yè)
郵箱：[email protected]
手機(jī)：18321818584 / 15026555973歡迎您關(guān)注我們的微信了解更多信息
掃一掃電話
微信掃一掃