簡要描述:Kelch樣蛋白2抗體免 疫 原;KLH conjugated synthetic peptide derived from human KLHL2: 1-100/593
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Kelch樣蛋白2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
Kelch樣蛋白2抗體 | KLHL2 | GOY-01K5125 |
商品屬性:
英文名稱: KLHL2
中文名:Kelch樣蛋白2抗體
別 名;ABP KELCH; Actin
binding protein Mayven; Actin-binding protein Mayven; kelch; kelch like 2;
Kelch like protein 2; Kelch-like protein 2; KLHL2; KLHL2_HUMAN; MAV; MAYVEN;
OTTHUMP00000219997; OTTHUMP00000219998.
研究領(lǐng)域;細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 結(jié)合蛋白 細(xì)胞骨架
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Rabbit, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;66kDa
細(xì)胞定位;細(xì)胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human KLHL2: 1-100/593
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
KLHL2 is a 593 amino acid actin-binding protein.
Highly expressed in brain, KLHL2 is thought to play a role in the
organization of the actin cytoskeleton in brain cells. KLHL3 (kelch-like
protein 3), is a 587 amino acid protein active in the protein ubiquitination
pathway. KLHL3 is thought to be a substrate-specific adapter of an E3
ubiquitin-ligase complex that mediates the ubiquitination of target proteins,
which leads to proteasomal degradation of the target protein. KLHL2 and KLHL3
proteins contain six kelch repeats and one BTB (POZ) domain. The BTB
(Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ
(Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain
that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers.
Proteins that contain BTB domains are thought to be involved in
transcriptional regulation via control of chromatin structure and function. May play a role in organizing the actin
cytoskeleton of the brain cells. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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