簡要描述:豬細小病毒VP2抗體免 疫 原;Recombinant Porcine Parvovirus VP2 protein
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豬細小病毒VP2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
豬細小病毒VP2抗體 | PPV VP2 | GOY-01K2067 |
商品屬性:
英文名稱: PPV VP2
中文名:豬細小病毒VP2抗體
別 名;PPV-VP2; Porcine
parvovirus VP2; PPV Isoform VP2 (P18546-2); Capsid protein VP1; CAPSD_PAVPN.
研究領(lǐng)域;免疫學 細菌及病毒
抗體來源;Rabbit
克隆類型;Polyclonal
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;64kDa
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;Recombinant
Porcine Parvovirus VP2 protein
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹:
Porcine Parvovirus Infection (PPV) is the most
common and important cause of infectious infertility. Porcine parvovirus is a
fairly tough virus that multiplies normally in the intestine of the pig
without causing clinical signs. It is world-wide in its distribution. If you
test for it in your pig herd it is almost certain it will be present unless
your herd is less than 100 sows when it might have died out. It is therefore
an infection you have to live with and manage. Whereas most viruses do not
survive outside the host for any great period of time PPV is unusual in that
it can persist outside the pig for many months and it is resistant to most
disinfectants. This perhaps explains why it is so widespread and so difficult
to remove from the pig environment. Function: Capsid protein self-assembles to form an
icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and
consisting of 60 copies of two size variants of the capsid proteins, VP1 and
VP2, which differ by the presence of an N-terminal extension in the minor
protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are
responsible for the attachment to host cell receptors. This attachment
induces virion internalization predominantly through clathrin-dependent
endocytosis. Binding to the host receptors also induces capsid rearrangements
leading to surface exposure of VP1 N-terminus, specifically its phospholipase
A2-like region and putative nuclear localization signal(s). VP1 N-terminus
might serve as a lipolytic enzyme to breach the endosomal membrane during
entry into host cell and might contribute to virus transport to the nucleus (By
similarity). |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學及檢測服務(wù):
我公司也為客戶提供單項免疫學和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標,主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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