簡要描述:mRNA前體剪接因子PRPF8抗體免 疫 原;KLH conjugated synthetic peptide derived from human PRPF8: 161-260/2335
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mRNA前體剪接因子PRPF8抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
mRNA前體剪接因子PRPF8抗體 | PRPF8 | GOY-01K5997 |
商品屬性:
英文名稱: PRPF8
中文名:mRNA前體剪接因子PRPF8抗體
別 名;220 kDa U5 snRNP specific
protein; 220 kDa U5 snRNP-specific protein; Apoptosis regulated protein 1;
Apoptosis regulated protein 2; HPRP8; p220; Pre mRNA processing factor 8; Pre
mRNA-processing factor 8, S. cerevisiae, homolog of;
Pre-mRNA-processing-splicing factor 8; Precursor mRNA processing protein; PRP8;
PRP8 homolog; PRP8 pre mRNA processing factor 8 homolog; PRP8_HUMAN; PRPC8;
Prpf8; Retinitis pigmentosa 13 (autosomal dominant); RP13; SNRNP220; Splicing
factor Prp8; U5 snRNP specific protein (220 kD), ortholog of S. cerevisiae
Prp8p; U5 snRNP specific protein.
研究領(lǐng)域;細(xì)胞生物 神經(jīng)生物學(xué) 干細(xì)胞 結(jié)合蛋白 表觀遺傳學(xué)
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, )
產(chǎn)品應(yīng)用;IHC-P=1:100-500
IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;274kDa
細(xì)胞定位;細(xì)胞核
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human PRPF8: 161-260/2335
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Pre-mRNA splicing occurs in 2 sequential transesterification
steps. The protein encoded by this gene is a component of both U2- and
U12-dependent spliceosomes, and found to be essential for the catalytic step
II in pre-mRNA splicing process. It contains several WD repeats, which
function in protein-protein interactions. This protein has a sequence
similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal
dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008] Functions as a scaffold that mediates the ordered
assembly of spliceosomal proteins and snRNAs. Required for the assembly of
the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions
spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so
that splicing can occur. Interacts with both the 5' and the 3' splice site. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺,能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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