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簡要描述：軸突導向因子SEMA6C抗體免 疫 原；KLH conjugated synthetic peptide derived from human SEMA6C: 256-305/930
產(chǎn)品型號：GOY-01K0633廠商性質：科研更新時間：2023-10-24 00:00:00訪 問 量：165產(chǎn)品分類
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軸突導向因子SEMA6C抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
軸突導向因子SEMA6C抗體 | SEMA6C | GOY-01K0633 |
商品屬性：
英文名稱: SEMA6C
中文名:軸突導向因子SEMA6C抗體
別 名；KIAA1869; m Sema
Y; m Sema Y2; sema domain, transmembrane domain (TM), and cytoplasmic domain,
(semaphorin) 6C; Sema Y antibody Semaphorin 6C [Precursor]; Semaphorin Y;
SEMAY; SEM6C_HUMAN.
研究領域；細胞生物 神經(jīng)生物學 細胞分化 細胞膜蛋白
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；(predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；97kDa
細胞定位；細胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human SEMA6C: 256-305/930
<Extracellular>
亞 型；IgG
純化方法；affinity
purified by Protein A
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Semaphorins are a family of cell surface and
secreted proteins involved in neural development that are conserved from
insects to humans. Members of this family are approximately 750 amino acids
in length (including signal sequences) and are defined by a conserved
extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16
cysteines, blocks of conserved sequences and no obvious repeats. The
transmembrane semaphorins are characterized by an additional 80 amino acid
transmembrane domain and an 80-110 amino acid cytoplasmic domain. SEMA6C,
also known as SEMA Y, is a transmembrane protein expressed in fetal brain and
adult skeletal muscle. Three isoforms of this semaphorin exist due to
alternative splicing: SEMA6C 1, SEMA6C 2 and SEMA6C 3. The extracellular
domain of SEMA6C induces growth cone collapse of dorsal root ganglion and
plays a role in generation or stability of entorhino-hippocampal synapses. Function: SEMA6C belongs to a subfamily characterized by an
extracellular semaphorin domain, a transmembrane domain, and a long
cytoplasmic tail. Members of this class can repel sympathetic and dorsal root
ganglion axons in vitro, consistent with a traditional role as guidance
signals. SEMA6C shows growth cone collapsing activity on dorsal root ganglion
(DRG) neurons in vitro and may be a stop signal for the DRG neurons in their
target areas, and possibly also for other neurons. SEMA6C may also be
involved in the maintenance and remodeling of neuronal connections. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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