簡(jiǎn)要描述:SH2結(jié)構(gòu)域蛋白3A抗體免 疫 原;KLH conjugated synthetic peptide derived from human NSP1/SH2D3A: 151-250/576
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SH2結(jié)構(gòu)域蛋白3A抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
SH2結(jié)構(gòu)域蛋白3A抗體 | SH2D3A | GOY-01K1456 |
商品屬性:
英文名稱: SH2D3A
中文名:SH2結(jié)構(gòu)域蛋白3A抗體
別 名;Novel SH2
containing protein 1; NSP1; SH2 domain containing 3A; SH2 domain containing
protein 3A; SH23A_HUMAN.
研究領(lǐng)域;腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 G蛋白偶聯(lián)受體
抗體來(lái)源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;63kDa
細(xì)胞定位;細(xì)胞核 細(xì)胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human NSP1/SH2D3A: 151-250/576
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
SH2D3A is a 576 amino acid protein that is thought
to play a role in JNK activation. SH2D3A interacts with p130 Cas and is found
at low levels in fetal kidney, fetal lung, placenta, adult pancreas, kidney
and lung. Subject to post-translational phosphorylation on multiple tyrosine
residues, SH2D3A contains one Src homology 2 (SH2) domain. SH2 domains bind
to tyrosine-phosphorylated regions of target proteins, frequently linking
activated growth factors to putative signal transduction proteins. The gene
encoding SH2D3A maps to human chromosome 19, which consists of over 63
million bases, houses approximately 1,400 genes and is recognized for having
the greatest gene density of the human chromosomes. It is the genetic home
for a number of immunoglobulin (Ig) superfamily members, including the killer
cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG
families and Fc receptors (FcRs). May play a role in JNK activation. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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