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內(nèi)質(zhì)網(wǎng)Aβ相關(guān)結(jié)合蛋白抗體

簡要描述:內(nèi)質(zhì)網(wǎng)Aβ相關(guān)結(jié)合蛋白抗體免 疫 原;KLH conjugated synthetic peptide derived from human ERAB: 51-130/196

  • 產(chǎn)品型號:GOY-01K1532
  • 廠商性質(zhì):科研
  • 更新時間:2023-10-24 00:00:00
  • 訪  問  量:199

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內(nèi)質(zhì)網(wǎng)Aβ相關(guān)結(jié)合蛋白抗體


產(chǎn)品名稱

英文名稱

貨號

內(nèi)質(zhì)網(wǎng)Aβ相關(guān)結(jié)合蛋白抗體

ERAB/HSD17B10

GOY-01K1532

商品屬性:

英文名稱: ERAB/HSD17B10

中文名:內(nèi)質(zhì)網(wǎng)Aβ相關(guān)結(jié)合蛋白抗體

    名;HSD17B10; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase; 17 beta hydroxysteroid dehydrogenase 10; 17 beta hydroxysteroid dehydrogenase type 10; 17b HSD10; 3 hydroxy 2 methylbutyryl CoA dehydrogenase; 3 hydroxyacyl CoA dehydrogenase type 2; 3 hydroxyacyl CoA dehydrogenase type II; AB binding alcohol dehydrogenase; ABAD; Ads9; Amyloid beta binding polypeptide; Amyloid beta peptide binding alcohol dehydrogenase; Amyloid beta peptide binding protein; CAMR; DUPXp11.22; Endoplasmic Reticulum Amyloid Binding Protein; Endoplasmic reticulum associated amyloid beta peptide binding protein; ER associated amyloid beta-binding protein; ERAB; HADH 2; HADH2; HCD 2; HCD2; HSD17B10; Hydroxyacyl CoA Dehydrogenase type II; Hydroxyacyl Coenzyme A dehydrogenase type II; Hydroxysteroid (17 beta) dehydrogenase 10; Mental retardation X linked syndromic 11; MHBD; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; MRPP2; MRX17; SCHAD; SDR5C1; Short chain dehydrogenase/reductase family 5C member 1; Short chain L 3 hydroxyacyl CoA dehydrogenase type 2; Short chain type dehydrogenase/reductase XH98G2; Type 10 17b HSD; Type 10 17beta hydroxysteroid dehydrogenase; Type II HADH; XH98G2.

研究領(lǐng)域;免疫學(xué)  神經(jīng)生物學(xué)  線粒體

抗體來源;Mouse

克隆類型;Polyclonal

交叉反應(yīng); (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, )

產(chǎn)品應(yīng)用;ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理論分子量;21kDa

細(xì)胞定位;細(xì)胞漿 線粒體

    狀;Liquid

    度;1mg/ml

免 疫 原;KLH conjugated synthetic peptide derived from human ERAB: 51-130/196

    型;IgG

純化方法;affinity purified by Protein A

緩 沖 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事項;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產(chǎn)品介紹:

This gene encodes 3-hydroxyacyl-CoA dehydrogenase  type II, a member of the short-chain dehydrogenase/reductase superfamily. The  gene product is a mitochondrial protein that catalyzes the oxidation of a  wide variety of fatty acids, alcohols, and steroids. The protein has been  implicated in the development of Alzheimer's disease, and mutations in the  gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency  (MHBD). Several alternatively spliced transcript variants have been  identified, but the full-length nature of only two transcript variants has  been determined. [provided by RefSeq, Jul 2008].

Functions in mitochondrial tRNA maturation. Part  of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1,  MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their  5'-ends. By interacting with intracellular amyloid-beta, it may contribute to  the neuronal dysfunction associated with Alzheimer disease (AD).

 

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多克隆抗體制備:

我公司合成抗原,保證陽性血清和抗體ELISA效價達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。

鼠單克隆抗體制備:

客戶可根據(jù)項目實際需求情況靈活選擇進(jìn)行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。

圖片1.png

重組抗體表達(dá)服務(wù):

重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺,能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。

單項免疫學(xué)及檢測服務(wù):

我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。

抗體定制服務(wù):

已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。

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