簡要描述:鈣加壓素2抗體免 疫 原;KLH conjugated synthetic peptide derived from human Calcipressin 2: 1-100/197
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鈣加壓素2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
鈣加壓素2抗體 | Calcipressin 2 | GOY-01K1787 |
商品屬性:
英文名稱: Calcipressin 2
中文名:鈣加壓素2抗體
別 名;DSCR1L1;
Calcipressin-2; CSP2; Down syndrome candidate region 1-like 1; Down syndrome
critical region gene 1 like 1 protein; MCIP2; Myocyte enriched calcineurin
interacting protein 2; Myocyte-enriched calcineurin-interacting protein 2;
RCAN2; RCAN2_HUMAN; RCN2; Regulator of calcineurin 2; Thyroid hormone
responsive protein ZAKI4; Thyroid hormone-responsive protein ZAKI-4; ZAKI4.
研究領(lǐng)域;心血管 細胞生物 染色質(zhì)和核信號 神經(jīng)生物學 信號轉(zhuǎn)導 細胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;22kDa
細胞定位;細胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH conjugated
synthetic peptide derived from human Calcipressin 2: 1-100/197
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Calcineurin is a Ca(2+) dependent protein
phosphatase that is involed in several neuornal functions. Proteins belonging
to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin
through a valine-rich region within their carboxyl tail. RCANs compete with
NFATs (Nuclear factor of activated T-cells) for binding to the same docking
site in calcineurin, which results in either inhibition or activation of
calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down
syndrome candidate region 1-like 1), is a 197 amino acid protein that is
highly expressed in both the cytoplasm and nucleus of neurons and is the only
RCAN family member that is found in glial cells. Calcipressin-3, also known
as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a
241 amino acid protein that potentially is involved in central nervous system
development. Calcipressin-3 interacts with cardiac troponin I, suggesting
that it may play a role in cardiac contraction events. Inhibits calcineurin-dependent transcriptional
responses by binding to the catalytic domain of calcineurin A. Could play a
role during central nervous system development. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學及檢測服務(wù):
我公司也為客戶提供單項免疫學和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標,主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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