簡(jiǎn)要描述:廣泛控制氨基酸合成1樣蛋白1抗體免 疫 原;KLH conjugated synthetic peptide derived from human Gcn1l1: 751-850/2671
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廣泛控制氨基酸合成1樣蛋白1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
廣泛控制氨基酸合成1樣蛋白1抗體 | Gcn1l1 | GOY-01K2377 |
商品屬性:
英文名稱: Gcn1l1
中文名:廣泛控制氨基酸合成1樣蛋白1抗體
別 名;GCN1; GCN1
(general control of amino acid synthesis yeast homolog) like; GCN1 (general
control of amino acid synthesis 1 yeast) like 1; GCN1 general control of amino
acid synthesis 1 like 1; GCN1 general control of amino acid synthesis 1 like 1
(yeast); GCN1 like protein 1; GCN1L; HsGCN1; GCN1L_HUMAN.
研究領(lǐng)域;細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來(lái)源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal dilutions/concentrations
should be determined by the end user.
理論分子量;293kDa
細(xì)胞定位;細(xì)胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human Gcn1l1: 751-850/2671
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
GCN1L1 is a 2,671 amino acid protein that is
ubiquitously expressed and belongs to the GCN1 family. Functioning as a
translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2
kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene
that maps to human chromosome 12q24.23. Chromosome 12 encodes over 1,100
genes and comprises approximately 4.5% of the human genome. Chromosome 12 is
associated with a variety of diseases and afflictions, including
hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and
trisomy 12p, which causes facial developmental defects and seizure disorders. Gcn1l1 acts as a translation activator which
mediates translational control and performs an EF3-related function on the
ribosome by regulating GCN2 protein kinase (EIF2AK1-4) activity. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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