產(chǎn)品分類
Product Category相關(guān)文章
Related Articles磷酸化自噬相關(guān)蛋白4A抗體注意事項;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
磷酸化自噬相關(guān)蛋白3抗體注意事項;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
磷酸化活化轉(zhuǎn)錄因子1抗體注意事項;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes.
歡迎您關(guān)注我們的微信了解更多信息
電話
微信掃一掃