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簡要描述：胞漿鈣獨(dú)立磷脂酶A2抗體免 疫 原；KLH conjugated synthetic peptide derived from human CaIPLA2: 331-430/806
產(chǎn)品型號：GOY-01K0109廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：165產(chǎn)品分類
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胞漿鈣獨(dú)立磷脂酶A2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
胞漿鈣獨(dú)立磷脂酶A2抗體 | CaIPLA2 | GOY-01K0109 |
商品屬性：
英文名稱: CaIPLA2
中文名:胞漿鈣獨(dú)立磷脂酶A2抗體
別 名；85 kDa calcium
independent phospholipase A2; 85 kDa calcium-independent phospholipase A2; CaI
PLA2; CaI-PLA2; CaIPLA2; Calcium independent phospholipase A2; Cytosolic
calcium independent phospholipase A2; Group VI phospholipase A2; GVI; GVI PLA2;
INAD1; iPLA(2)beta; iPLA2; IPLA2 VIA; iPLA2beta; NBIA2A; NBIA2B; PA2G6_HUMAN;
PARK14; Patatin like phospholipase domain containing 9; Patatin like
phospholipase domain containing protein 9; Phospholipase A2 calcium
independent; Phospholipase A2 calcium independent group VI A; Phospholipase A2
group VI; Phospholipase A2 group VI cytosolic calcium independent; PLA2;
PLA2G6; PNPLA9; PLPL9_HUMAN
研究領(lǐng)域；信號轉(zhuǎn)導(dǎo)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；Mouse,
Rat, (predicted: Human, Dog, Pig, Cow,
Rabbit, Sheep, )
產(chǎn)品應(yīng)用；IHC-P=1:100-500
IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；90kDa
細(xì)胞定位；細(xì)胞漿 細(xì)胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH conjugated
synthetic peptide derived from human CaIPLA2: 331-430/806
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The protein encoded by this gene is an A2
phospholipase, a class of enzyme that catalyzes the release of fatty acids
from phospholipids. The encoded protein may play a role in phospholipid remodelling,
arachidonic acid release, leukotriene and prostaglandin synthesis,
fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated
B-cells. Several transcript variants encoding multiple isoforms have been
described, but the full-length nature of only three of them have been
determined to date. [provided by RefSeq, Dec 2010]. Catalyzes the release of fatty acids from
phospholipids. It has been implicated in normal phospholipid remodeling,
nitric oxide-induced or vasopressin-induced arachidonic acid release and in
leukotriene and prostaglandin production. May participate in fas mediated
apoptosis and in regulating transmembrane ion flux in glucose-stimulated
B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed
and directionality of monocyte MCP1/CCL2-induced chemotaxis through
regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform
ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in
the negative regulation of iPLA2 activity. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報價，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報價，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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